![]() 5 The potential effects of miR-143 and miR-135a on signaling pathways. Some loci were reported only in Chinese populations (loci shown in black) or in both Chinese populations and other ethnic populations (loci shown in red).įig. ![]() 4 Susceptibility loci of AR in Chinese population studies. AR, allergic rhinitis SPT, skin prick test IgE, immunoglobulin E NPT, nasal provocation test LAR, local allergic rhinitis NAR, non-allergic rhinitis sIgE, serum-specific IgE.įig. 2 The prevalence of sensitization to dust mites in China.įig. 1 Prevalence of adult AR in major cities in China in 20.įig. These guidelines have been prepared in line with existing international guidelines to provide evidence-based recommendations for the diagnosis and management of AR in China.įig. Thus, the present guidelines have been developed by the Chinese Society of Allergy to be accessible to both national and international medical communities involved in the management of AR patients. ![]() Moreover, methods for the diagnosis and treatment of AR in China have not been standardized entirely and some patients are still treated according to regional preferences. Although guidelines for the diagnosis and treatment of AR in Chinese subjects have also been published, they have not been translated into English and therefore not generally accessible for reference to non-Chinese speaking international medical communities. An increasing number of original articles and imporclinical trials on the epidemiology, pathophysiologic mechanisms, diagnosis, management and comorbidities of AR in Chinese subjects have been published in international peer-reviewed journals over the past 2 decades, and substantially added to our understanding of this disease as a global problem. A survey of self-reported AR over a 6-year period in the general Chinese adult population reported that the standardized prevalence of adult AR increased from 11.1% in 2005 to 17.6% in 2011. Likewise, a rising trend of AR has also been observed over the last 2-3 decades in developing countries including China, with the prevalence of AR varying widely in these countries. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries and currently affects up to 40% of the population worldwide. 19Department of Otorhinolaryngology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, China.Ībstract Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide.18Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji University, Shanghai, China.17Department of Otorhinolaryngology, Affiliated Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.16Department of Traditional Chinese Medicine, Beijing TongRen Hospital, Capital Medical University, Beijing, China.15Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.14Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China. ![]() 13Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China. 12Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.11Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital, Fudan University, Shanghai, China. ![]()
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